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Saturday, 24 April 2010 20:46

Leibniz-Institut für
Molekulare Pharmakologie

The institute is a member of the Leibniz-Association and is legally represented by the Forschungsverbund Berlin e.V.

FMP research focusses on the structures, functions and interactions of proteins and on the development of new concepts for interfering pharmacologically with their functions. This places the research activity of the institute at the forefront of drug development. An interdisciplinary approach is crucial to this type of work, and a particular strength of the FMP is the close interaction in the fields
of chemistry and biology.

The Klussmann lab at the Leibniz Institute of Molecular Pharmacology, a strong interdisciplinary team focussed on the discovery and development of pharmaceutical candidates in the field of cardiovascular therapy, is looking for a

PhD student

for immediate employment in our Berlin-Buch research facility.

Our group is studying compartmentalized cAMP signalling in renal principal cells and cardiac myocytes. In renal principal cells, we are aiming to identify and characterize molecular mechanisms and proteins underlying the vasopressin-triggered redistribution of aquaporin-2 (AQP2) from intracellular vesicles into the plasma membrane. This process is essential for the reabsorption of water and involved in pathophysiology of diseases such as chronic heart failure. We offer a PhD student position to a candidate motivated to search for new proteins required for the redistribution of AQP2. The project requires proteome-wide RNAi - and small molecule screens using the high throughput screening facility of the institute, cloning techniques, analyses of protein-protein interactions, protein biochemistry, fluorescence microscopy (laser scanning microscopy, FRET), and the use of small molecules as tools to reach the goals.
The institute is located on the Berlin-Buch Campus, a unique cluster of excellent biomedical and clinical research facilities and one of the strongest centres of scientific excellence in Europe. The campus is about 30 mins from the centre of Berlin, known for its rich cultural life and high quality of life. Berlin is one of the most affordable large cities of the world.
The position is funded for 3 years and will be remunerated at German public service rates (TVöD).
Interested candidates (biologists, biochemists, pharmacists or other life sciences) please apply until 22 May providing CV, publication list and addresses of two referees by e.-mail to:

Leibniz-Institut für Molekulare Pharmakologie
Katrin Schubert
Robert-Rössle-Str. 10
13125 Berlin
Germany

Department of Signal transduction / Molecular Medicine
Dr. Enno Klussmann:
Tel.: +49-30-94793 260 / 349
E.-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it


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Von:

Katrin Schubert
This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Forschungsverbund Berlin e.V., FMP
13125 Berlin

Ansprechpartner: Katrin Schubert

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