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PhD in Systems Biology, AFR grant (M/F) PDF Print E-mail
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Saturday, 24 April 2010 20:46

Fachgebiete: Biologie Informatik
Thema: Doktorarbeit: PhD in Systems Biology, AFR grant (M/F)
Ansprechpartner: Prof. Thomas Sauter
Antwort an: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Institution: University of Luxembourg
Ort: L1511 Luxembourg, 162A, Av. Faiencerie

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The University of Luxembourg is looking within the Life Sciences Research Unit (LSRU) of its Faculty of Science, Technology and Communication for a:
PhD student in systems biology (M/F)
2-year fixed term contract, renewable 2 years, beginning January 1st, 2010 at the earliest
AFR (Aide à la formation recherche) Grant

The objective of the Life Sciences Research Unit (LSRU) is to implement and to use systems biology approaches to gain further insights in characteristics of inflammatory processes occurring in Alzheimer's disease, the metabolic syndrome and cancer. Diseases occur not only from an internal dysfunction of the complex constitutive interactions between genes, their expression products and their functions, but also from numerous external disturbing interferences, e.g. exposure to cytokines or to a variety of environmental factors, including nutrients originating from food intake.
A lifetime exposure to micronutrients and cytokines may therefore be part of a central molecular process towards atherosclerosis. We propose here a feasibility study, in view to adapt the competences and possible techniques of the LSRU to a Medium Throughput Screening concept and to collect genomic, transcriptomic, simple proteomic and functional data from wet lab in vitro cellular inflammation processes, in order to evidence new genetic biomarkers in atherosclerosis. We will use systems biology and bioinformatics approaches to unify data derived from our own experiments and others reported in the literature and databases with clinical data, to generate in silico models of nuclear receptor and NF-kappaB pathways in metabolism, cellular regulation and inflammation.

Profil
Master in Bioinformatics / Biology or equal required
Knowledge in bioinformatics and experience in wet lab and genome biology are desired
Good knowledge in English
Additional French and/or German would be ideal

Application End: 05 July 2009
The University of Luxembourg is an equal opportunity employer.


Anfangsdatum: 1. Januar 2009

geschätzte Dauer: 2 + 2 years

Bezahlung: ca. 2500 Euro / month

Homepage: http://wwwde.uni.lu/forschung/fstc/life_sciences_research_unit

Prof. Dr. Jean-Luc Bueb
E-Mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
University of Luxembourg, Life Sciences Research Unit: Systems Biology
162 A, avenue de la Faïencerie
L-1511 Luxembourg

Please send your motivation letter, CV, scanned diplomas and references files until July 5th,2009 to:
Prof. Jean-Luc Bueb ( This e-mail address is being protected from spambots. You need JavaScript enabled to view it )

*http://jobs.uni-hd.de
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