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Saturday, 07 August 2010 18:01

Fachgebiete: Biologie Humanmedizin Tiermedizin
Thema: Doktorarbeit / Diplomarbeit: PhD Position in Neural Stem Cell Biology
Ansprechpartner: Dr. rer. nat. Jens Schwamborn
Antwort an: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Institution: Stem Cell Biology and Regeneration group
Ort: 48149 Münster, Von-Esmarch-Str. 56

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Applications are invited for a position within the group of Dr. Jens Schwamborn to investigate the mechanisms of fate specification in neural stem cells.
We investigate how the proliferation and differentiation of adult neural stem cells is regulated. In particular, we are interested in the question how the grade of differentiation of a cell is determined and how stem cell maintenance works. Further on we try to find ways to reprogram differentiated cells back into somatic stem cells. The overall aim of our work is to make endogenously present adult neural stem cells applicable for therapeutic approaches aiming for the replacement of neurons that are lost during neurodegenerative diseases (e.g. Parkinson’s disease)
Successful applicants should have a strong interest in Cell and Neurobiology, particularly experience in Stem Cell Biology would be a plus. We are looking for highly motivated people who share our passion for research, are interested in aquiring new skills and wish to be part of an international team.
Please send your application via E-Mail to: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Dr. Jens C. Schwamborn
Westfälische Wilhelms-Universität Münster
ZMBE, Institute of Cell Biology
Stem Cell Biology and Regeneration group
Von-Esmarch-Str. 56
48149 Münster
Germany
Phone: +49-251-83-57183
E-Mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Web: http://zmbe.uni-muenster.de/institutes/izb/stemres_de.htm


Methoden:
Stem Cell Cultures
iPS Technology
Confocal Microscopy
Mouse Genetics and other Mouse in vivo methods
Full spectrum of techniques from cell biology and neurobiology


Anfangsdatum: 15. Oktober 2010

geschätzte Dauer: 3 years

Bezahlung: TVL E13/2

Homepage: http://zmbe.uni-muenster.de/institutes/izb/stemres_de.htm

Schwamborn J.C., Berizikov E., Knoblich J. (2009). The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell 136, 913-25

Wen L., Schwamborn J.C. (2009). Reprogramming and its implications for therapeutic applications. Euro Pharm Rev 3, 36-40

Palm T., Schwamborn J.C. (2010) Brain Tumor Stem Cells. Biol. Chem. 6, 607-17

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